Optimized Adenoviral Vector That Enhances the Assembly of FMDV O1 Virus-Like Particles in situ Increases Its Potential as Vaccine for Serotype O Viruses

Optimized Adenoviral Vector That Enhances the Assembly of FMDV O1 Virus-Like Particles in situ Increases Its Potential as Vaccine for Serotype O Viruses

Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding region of foot-and-mouth disease virus (FMDV) have been proven to be effective as vaccines in relevant species for several viral strains, the same result was not consistently achieved for th...

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Bibliographic Details
Main Authors:	Micaela Ziraldo, Juan E. Bidart, Cecilia A. Prato, María V. Tribulatti, Patricia Zamorano, Nora Mattion, Alejandra L. D’Antuono
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Microbiology
Subjects:	foot-and-mouth disease virus replication-defective human adenovirus type 5 genetic vaccine mutated VP2 capsid protein virus-like particles O1/Campos neutralizing antibodies
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2020.591019/full

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