Intestinal microbiota in the pathogenesis of chronic heart failure

In this review, we have considered and discussed the existing data to achieve a deeper understanding of the role of intestinal microbiota in the development and progression of chronic heart failure (CHF). The key moments of the CHF pathogenesis (an imbalance of neurohumoral systems, inflammatory th...

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Main Authors: Vladimir Ivashkin, Maria Fadeeva, Manana Skhirtladze, Oxana Zolnikova
Format: Article
Language:English
Published: PAGEPress Publications 2020-03-01
Series:Italian Journal of Medicine
Subjects:
Online Access:https://www.italjmed.org/index.php/ijm/article/view/1185
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spelling doaj-3bbf5001995343b2968d8bd6a04647572020-11-25T03:19:32ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522020-03-0114110.4081/itjm.2020.1185Intestinal microbiota in the pathogenesis of chronic heart failureVladimir Ivashkin0Maria Fadeeva1Manana Skhirtladze2Oxana Zolnikova3Internal Disease Propedeutics, I.M. Sechenov First Moscow State Medical University, MoscowVasilenko Clinic of Internal Disease Propedeutics, Gastroenterology, and Hepatology, I.M. Sechenov First Moscow State Medical University, MoscowVasilenko Clinic of Internal Disease Propedeutics, Gastroenterology, and Hepatology, I.M. Sechenov First Moscow State Medical University, MoscowInternal Disease Propedeutics, I.M. Sechenov First Moscow State Medical University, Moscow In this review, we have considered and discussed the existing data to achieve a deeper understanding of the role of intestinal microbiota in the development and progression of chronic heart failure (CHF). The key moments of the CHF pathogenesis (an imbalance of neurohumoral systems, inflammatory theory and metabolic disorders) and the respective changes of the intestinal microflora composition were compared. Here, we also present the latest results of the positive influence of the microflora modulations on the course and prognosis of CHF with the prescribing antibiotics, probiotics and prebiotics. https://www.italjmed.org/index.php/ijm/article/view/1185Intestinal microbiotachronic heart failureprobioticscytokines.
collection DOAJ
language English
format Article
sources DOAJ
author Vladimir Ivashkin
Maria Fadeeva
Manana Skhirtladze
Oxana Zolnikova
spellingShingle Vladimir Ivashkin
Maria Fadeeva
Manana Skhirtladze
Oxana Zolnikova
Intestinal microbiota in the pathogenesis of chronic heart failure
Italian Journal of Medicine
Intestinal microbiota
chronic heart failure
probiotics
cytokines.
author_facet Vladimir Ivashkin
Maria Fadeeva
Manana Skhirtladze
Oxana Zolnikova
author_sort Vladimir Ivashkin
title Intestinal microbiota in the pathogenesis of chronic heart failure
title_short Intestinal microbiota in the pathogenesis of chronic heart failure
title_full Intestinal microbiota in the pathogenesis of chronic heart failure
title_fullStr Intestinal microbiota in the pathogenesis of chronic heart failure
title_full_unstemmed Intestinal microbiota in the pathogenesis of chronic heart failure
title_sort intestinal microbiota in the pathogenesis of chronic heart failure
publisher PAGEPress Publications
series Italian Journal of Medicine
issn 1877-9344
1877-9352
publishDate 2020-03-01
description In this review, we have considered and discussed the existing data to achieve a deeper understanding of the role of intestinal microbiota in the development and progression of chronic heart failure (CHF). The key moments of the CHF pathogenesis (an imbalance of neurohumoral systems, inflammatory theory and metabolic disorders) and the respective changes of the intestinal microflora composition were compared. Here, we also present the latest results of the positive influence of the microflora modulations on the course and prognosis of CHF with the prescribing antibiotics, probiotics and prebiotics.
topic Intestinal microbiota
chronic heart failure
probiotics
cytokines.
url https://www.italjmed.org/index.php/ijm/article/view/1185
work_keys_str_mv AT vladimirivashkin intestinalmicrobiotainthepathogenesisofchronicheartfailure
AT mariafadeeva intestinalmicrobiotainthepathogenesisofchronicheartfailure
AT mananaskhirtladze intestinalmicrobiotainthepathogenesisofchronicheartfailure
AT oxanazolnikova intestinalmicrobiotainthepathogenesisofchronicheartfailure
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