Intestinal microbiota in the pathogenesis of chronic heart failure

In this review, we have considered and discussed the existing data to achieve a deeper understanding of the role of intestinal microbiota in the development and progression of chronic heart failure (CHF). The key moments of the CHF pathogenesis (an imbalance of neurohumoral systems, inflammatory th...

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Bibliographic Details
Main Authors: Vladimir Ivashkin, Maria Fadeeva, Manana Skhirtladze, Oxana Zolnikova
Format: Article
Language:English
Published: PAGEPress Publications 2020-03-01
Series:Italian Journal of Medicine
Subjects:
Online Access:https://www.italjmed.org/index.php/ijm/article/view/1185
Description
Summary:In this review, we have considered and discussed the existing data to achieve a deeper understanding of the role of intestinal microbiota in the development and progression of chronic heart failure (CHF). The key moments of the CHF pathogenesis (an imbalance of neurohumoral systems, inflammatory theory and metabolic disorders) and the respective changes of the intestinal microflora composition were compared. Here, we also present the latest results of the positive influence of the microflora modulations on the course and prognosis of CHF with the prescribing antibiotics, probiotics and prebiotics.
ISSN:1877-9344
1877-9352