Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies

Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies

Abstract Background Artemisinin-based combination therapy (ACT) is used as the first-line treatment of uncomplicated malaria caused by the Plasmodium falciparum parasite and chloroquine-resistant Plasmodium vivax parasites. Evidence of resistance to ACT has been reported in Cambodia, and without new...

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Bibliographic Details
Main Authors: Guilherme Eduardo de Souza, Renata Vieira Bueno, Juliana Oliveira de Souza, Camila Lima Zanini, Fábio Cardoso Cruz, Glaucius Oliva, Rafael Victório Carvalho Guido, Anna Caroline Campos Aguiar
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Malaria Journal
Subjects:
Antimalarial
Drug resistance
Combination therapy
Drug development
Malaria Box
Online Access:https://doi.org/10.1186/s12936-019-3069-3

Internet

https://doi.org/10.1186/s12936-019-3069-3

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