Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes.

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes.

Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate adaptive immune responses to antigens delivered via afferent lymphatic vessels. Lymphatic endothelial cells (LECs) line intranodal lymphatic sinuses and organize lymph and antigen distribution. LECs also directly regulate...

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Bibliographic Details
Main Authors: Noriki Fujimoto, Yuliang He, Marco D'Addio, Carlotta Tacconi, Michael Detmar, Lothar C Dieterich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000704

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