Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis

Multiple sclerosis (MS) is a neuro-autoimmune and neurodegenerative disorder leading to chronic inflammation, demyelination, axonal, and neuronal loss in the central nervous system (CNS). Despite intense research efforts, the pathogenesis of MS still remains unclear. Toll-like receptors (TLRs) are a...

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Bibliographic Details
Main Authors: Chao Zheng, Jingtao Chen, Fengna Chu, Jie Zhu, Tao Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00314/full