Gastrodin Alleviates Cognitive Dysfunction and Depressive-Like Behaviors by Inhibiting ER Stress and NLRP3 Inflammasome Activation in db/db Mice

Gastrodin Alleviates Cognitive Dysfunction and Depressive-Like Behaviors by Inhibiting ER Stress and NLRP3 Inflammasome Activation in db/db Mice

Patients with diabetes mellitus (DM) suffer more risks from diabetic encephalopathy such as cognitive dysfunction and depressive-like behaviors. Numerous studies show that ER (endoplasmic reticulum) stress and inflammation play important roles in the development of diabetic encephalopathy. <i>...

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Bibliographic Details
Main Authors: Tianyuan Ye, Xiangbao Meng, Ruiying Wang, Chenyang Zhang, Shuaibing He, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic encephalopathy
Gastrodin
NLRP3 inflammasome
ER stress
Online Access:https://www.mdpi.com/1422-0067/19/12/3977

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