An Experimental Study on [125I]I-pHLIP (Var7) for SPECT/CT Imaging of an MDA-MB-231 Triple-Negative Breast Cancer Mouse Model by Targeting the Tumor Microenvironment

An Experimental Study on [125I]I-pHLIP (Var7) for SPECT/CT Imaging of an MDA-MB-231 Triple-Negative Breast Cancer Mouse Model by Targeting the Tumor Microenvironment

Objective. To evaluate the diagnostic efficacy of MDA-MB-231 triple-negative breast cancer with 125I-labeled pHLIP (Var7) by single-photon emission computed tomography/computed tomography (SPECT/CT) imaging. Methods. The binding fraction of [125I]I-pHLIP (Var7) and MDA-MB-231 cells was measured at p...

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Bibliographic Details
Main Authors: Mingming Yu, Yanqin Sun, Guangjie Yang, Zhenguang Wang
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2021-01-01
Series:Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2021/5565932

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