“Oxygen sensing” by Na,K-ATPase: these miraculous thiols

Control over the Na,K-ATPase function plays a central role in adaptation of the organisms to hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its oxygen-sensitivity is mediated by a variety of redox-sensitive modifications including S-glutathionylation, S-nitrosy...

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Bibliographic Details
Main Authors: Anna Bogdanova, Irina Yu Petrushanko, Pablo Hernansanz-Agustín, Antonio Martínez-Ruiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00314/full