First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters

First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters

Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/...

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Main Authors: Mara Bruzzi, Cinzia Talamonti, Nicola Calisi, Stefano Caporali, Anna Vinattieri
Format: Article
Language:English
Published: AIP Publishing LLC 2019-05-01
Series:APL Materials
Online Access:http://dx.doi.org/10.1063/1.5083810
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spelling doaj-3b7ed65f1cdb43e284c4f7940d3953f42020-11-24T23:55:35ZengAIP Publishing LLCAPL Materials2166-532X2019-05-0175051101051101-610.1063/1.5083810020904APMFirst proof-of-principle of inorganic perovskites clinical radiotherapy dosimetersMara Bruzzi0Cinzia Talamonti1Nicola Calisi2Stefano Caporali3Anna Vinattieri4Università degli Studi di Firenze, Dipartimento di Fisica ed Astronomia, Via G. Sansone 1, 50019 Sesto Fiorentino, Firenze, ItalyIstituto Nazionale di Fisica Nucleare, Sezione di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino, Firenze, ItalyUniversità degli Studi di Firenze, Dipartimento di Ingegneria Industriale, Via S. Marta 3, 50139 Firenze, ItalyUniversità degli Studi di Firenze, Dipartimento di Ingegneria Industriale, Via S. Marta 3, 50139 Firenze, ItalyUniversità degli Studi di Firenze, Dipartimento di Fisica ed Astronomia, Via G. Sansone 1, 50019 Sesto Fiorentino, Firenze, ItalyInorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/min of interest for clinical applications. A device sensitivity of about 70 nC/Gy mm3 compares favorably with other solid-state dosimeters. The first verification of an IMRT dose profile of a prostate cancer treatment, performed by moving the perovskite device on a 10 cm-long profile with a 0.5 mm pitch, showed agreement within 5% with the dose distribution required by the treatment planning system.http://dx.doi.org/10.1063/1.5083810
collection DOAJ
language English
format Article
sources DOAJ
author Mara Bruzzi
Cinzia Talamonti
Nicola Calisi
Stefano Caporali
Anna Vinattieri
spellingShingle Mara Bruzzi
Cinzia Talamonti
Nicola Calisi
Stefano Caporali
Anna Vinattieri
First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
APL Materials
author_facet Mara Bruzzi
Cinzia Talamonti
Nicola Calisi
Stefano Caporali
Anna Vinattieri
author_sort Mara Bruzzi
title First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
title_short First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
title_full First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
title_fullStr First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
title_full_unstemmed First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
title_sort first proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
publisher AIP Publishing LLC
series APL Materials
issn 2166-532X
publishDate 2019-05-01
description Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/min of interest for clinical applications. A device sensitivity of about 70 nC/Gy mm3 compares favorably with other solid-state dosimeters. The first verification of an IMRT dose profile of a prostate cancer treatment, performed by moving the perovskite device on a 10 cm-long profile with a 0.5 mm pitch, showed agreement within 5% with the dose distribution required by the treatment planning system.
url http://dx.doi.org/10.1063/1.5083810
work_keys_str_mv AT marabruzzi firstproofofprincipleofinorganicperovskitesclinicalradiotherapydosimeters
AT cinziatalamonti firstproofofprincipleofinorganicperovskitesclinicalradiotherapydosimeters
AT nicolacalisi firstproofofprincipleofinorganicperovskitesclinicalradiotherapydosimeters
AT stefanocaporali firstproofofprincipleofinorganicperovskitesclinicalradiotherapydosimeters
AT annavinattieri firstproofofprincipleofinorganicperovskitesclinicalradiotherapydosimeters
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