COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil

COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil

COVID-19 pandemic has been a problem worldwide. It is important to identify people at risk of progressing to severe complications and to investigate if some existing antivirals could have any action against SARS-CoV-2. In this context, HIV-infected individuals and antiretroviral drugs might be inclu...

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Bibliographic Details
Main Authors: Murillo Machado Cipolat, Eduardo Sprinz
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Brazilian Journal of Infectious Diseases
Subjects:
SARS-CoV-2
COVID-19
HIV
AIDS
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867020301082
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spelling doaj-3b7e0b12723e49d19a413700081454082020-11-25T03:34:42ZengElsevierBrazilian Journal of Infectious Diseases1413-86702020-09-01245455457COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, BrazilMurillo Machado Cipolat0Eduardo Sprinz1Hospital de Clínicas de Porto Alegre, Infectious Diseases Service, Porto Alegre, RS, BrazilHospital de Clínicas de Porto Alegre, Infectious Diseases Service, Porto Alegre, RS, Brazil; Universidade Federal de Rio Grande do Sul, Faculdade de Medicina, Porto Alegre, RS, Brazil; Corresponding author.COVID-19 pandemic has been a problem worldwide. It is important to identify people at risk of progressing to severe complications and to investigate if some existing antivirals could have any action against SARS-CoV-2. In this context, HIV-infected individuals and antiretroviral drugs might be included, respectively. Herein we present the case of a 63-year-old HIV-infected woman with undetectable viral load, on dolutegravir, tenofovir and lamivudine, who was hospitalized due to COVID-19 pneumonia. In spite of having some clinical markers of severity on admission, the patient improved and was discharged after a week. To our knowledge, this is the first report of severe SARS-CoV-2 infection in an HIV-infected individual in Brazil.http://www.sciencedirect.com/science/article/pii/S1413867020301082SARS-CoV-2COVID-19HIVAIDS
collection DOAJ
language English
format Article
sources DOAJ
author Murillo Machado Cipolat
Eduardo Sprinz
spellingShingle Murillo Machado Cipolat
Eduardo Sprinz
COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
Brazilian Journal of Infectious Diseases
SARS-CoV-2
COVID-19
HIV
AIDS
author_facet Murillo Machado Cipolat
Eduardo Sprinz
author_sort Murillo Machado Cipolat
title COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_short COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_full COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_fullStr COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_full_unstemmed COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_sort covid-19 pneumonia in an hiv-positive woman on antiretroviral therapy and undetectable viral load in porto alegre, brazil
publisher Elsevier
series Brazilian Journal of Infectious Diseases
issn 1413-8670
publishDate 2020-09-01
description COVID-19 pandemic has been a problem worldwide. It is important to identify people at risk of progressing to severe complications and to investigate if some existing antivirals could have any action against SARS-CoV-2. In this context, HIV-infected individuals and antiretroviral drugs might be included, respectively. Herein we present the case of a 63-year-old HIV-infected woman with undetectable viral load, on dolutegravir, tenofovir and lamivudine, who was hospitalized due to COVID-19 pneumonia. In spite of having some clinical markers of severity on admission, the patient improved and was discharged after a week. To our knowledge, this is the first report of severe SARS-CoV-2 infection in an HIV-infected individual in Brazil.
topic SARS-CoV-2
COVID-19
HIV
AIDS
url http://www.sciencedirect.com/science/article/pii/S1413867020301082
work_keys_str_mv AT murillomachadocipolat covid19pneumoniainanhivpositivewomanonantiretroviraltherapyandundetectableviralloadinportoalegrebrazil
AT eduardosprinz covid19pneumoniainanhivpositivewomanonantiretroviraltherapyandundetectableviralloadinportoalegrebrazil
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