The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females

The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females

Abstract Background Primary glomerulonephritis (GN) is the leading cause of chronic kidney disease (CKD) and frequently progresses into end stage renal diseases (ESRDs). Shorter leukocyte telomere length (LTL) has been implicated in the CKD susceptibility and diminished kidney function, however, it...

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Bibliographic Details
Main Authors: Qing Sun, Junli Liu, Guanghui Cheng, Mingkai Dai, Jiaxi Liu, Zhenqiang Qi, Jingjie Zhao, Wei Li, Feng Kong, Gang Liu, Magnus Björkholm, Dawei Xu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Translational Medicine
Subjects:
CKD
Genotypes
Glomerulonephritis
Single nucleotide polymorphism
Telomerase
Telomere
Online Access:http://link.springer.com/article/10.1186/s12967-020-02347-3

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