Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines
A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2007-02-01
|
| Series: | Beilstein Journal of Organic Chemistry |
| Online Access: | https://doi.org/10.1186/1860-5397-3-8 |
| id |
doaj-3b75263d6e57469b805bd6b43306242c |
|---|---|
| record_format |
Article |
| spelling |
doaj-3b75263d6e57469b805bd6b43306242c2021-02-02T00:30:43ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972007-02-0131810.1186/1860-5397-3-81860-5397-3-8Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidinesOlivier Y. Provoost0Andrew J. Hazelwood1Joseph P. A. Harrity2Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, S3 7HF, UKSynthetic Chemistry, GlaxoSmithKline Research and Development, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UKDepartment of Chemistry, University of Sheffield, Brook Hill, Sheffield, S3 7HF, UKA [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.https://doi.org/10.1186/1860-5397-3-8 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Olivier Y. Provoost Andrew J. Hazelwood Joseph P. A. Harrity |
| spellingShingle |
Olivier Y. Provoost Andrew J. Hazelwood Joseph P. A. Harrity Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines Beilstein Journal of Organic Chemistry |
| author_facet |
Olivier Y. Provoost Andrew J. Hazelwood Joseph P. A. Harrity |
| author_sort |
Olivier Y. Provoost |
| title |
Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines |
| title_short |
Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines |
| title_full |
Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines |
| title_fullStr |
Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines |
| title_full_unstemmed |
Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines |
| title_sort |
pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines |
| publisher |
Beilstein-Institut |
| series |
Beilstein Journal of Organic Chemistry |
| issn |
1860-5397 |
| publishDate |
2007-02-01 |
| description |
A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol. |
| url |
https://doi.org/10.1186/1860-5397-3-8 |
| work_keys_str_mv |
AT olivieryprovoost pdcatalysed33annelationsinthestereoselectivesynthesisofindolizidines AT andrewjhazelwood pdcatalysed33annelationsinthestereoselectivesynthesisofindolizidines AT josephpaharrity pdcatalysed33annelationsinthestereoselectivesynthesisofindolizidines |
| _version_ |
1724313592741756928 |