Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines

A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.

Bibliographic Details
Main Authors: Olivier Y. Provoost, Andrew J. Hazelwood, Joseph P. A. Harrity
Format: Article
Language:English
Published: Beilstein-Institut 2007-02-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.1186/1860-5397-3-8