Proprotein convertase 1/3-mediated down-regulation of brain-derived neurotrophic factor in cortical neurons induced by oxygen-glucose deprivation
Brain-derived neurotrophic factor (BDNF) has robust effects on synaptogenesis, neuronal differentiation and synaptic transmission and plasticity. The maturation of BDNF is a complex process. Proprotein convertase 1/3 (PC1/3) has a key role in the cleavage of protein precursors that are directed to r...
Main Authors: | Xiang-Yang Zhang, Feng Liu, Yan Chen, Wei-Chun Guo, Zhao-Hui Zhang |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2020-01-01
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Series: | Neural Regeneration Research |
Subjects: | |
Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1066;epage=1070;aulast=Zhang |
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