Neurons Generated by Mouse ESCs with Hippocampal or Cortical Identity Display Distinct Projection Patterns When Co-transplanted in the Adult Brain
Summary: The capability of generating neural precursor cells with distinct types of regional identity in vitro has recently opened new opportunities for cell replacement in animal models of neurodegenerative diseases. By manipulating Wnt and BMP signaling, we steered the differentiation of mouse emb...
Main Authors: | Marco Terrigno, Irene Busti, Claudia Alia, Marta Pietrasanta, Ivan Arisi, Mara D'Onofrio, Matteo Caleo, Federico Cremisi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-03-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671118300365 |
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