Vitamin B Deficiency Does not Affect the Liver Concentrations of the Other Seven Kinds of B-Group Vitamins in Rats

We aimed to determine the effects of vitamin B 1 deficiency on vitamin contents of urine, liver, and blood. In the current study, rats were divided into 3 groups (n = 5, each group): the first was freely fed a complete diet (ad lib-fed control group); the second freely fed a vitamin B 1 -free diet (...

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Bibliographic Details
Main Authors: Katsumi Shibata, Atsushi Shimizu, Tsutomu Fukuwatari
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:Nutrition and Metabolic Insights
Online Access:https://doi.org/10.4137/NMI.S11749
Description
Summary:We aimed to determine the effects of vitamin B 1 deficiency on vitamin contents of urine, liver, and blood. In the current study, rats were divided into 3 groups (n = 5, each group): the first was freely fed a complete diet (ad lib-fed control group); the second freely fed a vitamin B 1 -free diet (vitamin B 1 deficient group); and the third pair-fed a complete diet with the same amounts of the vitamin B 1 deficient group (pair-fed control group). The experimental period was for 15 days. The blood concentrations of vitamin B 2 , PLP, vitamin B 12 , folic acid, and biotin were lower in the pair-fed control than in the ad lib-fed control and those of nicotinamide and pantothenic acid were the same. We conclude that Vitamin B 1 deficiency did not affect concentrations of the other B-group vitamins.
ISSN:1178-6388