Human oligodendrocytes express Cx31.3: Function and interactions with Cx32 mutants

Human oligodendrocytes express Cx31.3: Function and interactions with Cx32 mutants

Murine oligodendrocytes express the gap junction (GJ) proteins connexin32 (Cx32), Cx47, and Cx29. CNS phenotypes in patients with X-linked Charcot–Marie–Tooth disease may be caused by dominant effects of Cx32 mutations on other connexins. Here we examined the expression of Cx31.3 (the human ortholog...

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Bibliographic Details
Main Authors: Irene Sargiannidou, Meejin Ahn, Alan D. Enriquez, Alejandro Peinado, Richard Reynolds, Charles Abrams, Steven S. Scherer, Kleopas A. Kleopa
Format: Article
Language:English
Published: Elsevier 2008-05-01
Series:Neurobiology of Disease
Subjects:
CMT1X
Connexin29
Gap junctions
Protein trafficking, Hemichannels
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000181

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