Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells.

Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells.

Currently, cardiomyocyte (CM) differentiation methods require a purification step after CM induction to ensure the high purity of the cell population. Here we show an improved human CM differentiation protocol with which high-purity ventricular-type CMs can be obtained and maintained without any CM...

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Bibliographic Details
Main Authors: Hiroyuki Fukushima, Miki Yoshioka, Masahide Kawatou, Víctor López-Dávila, Masafumi Takeda, Yasunari Kanda, Yuko Sekino, Yoshinori Yoshida, Jun K Yamashita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241287

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https://doi.org/10.1371/journal.pone.0241287

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