Superoxide Dismutase 3-Transduced Mesenchymal Stem Cells Preserve Epithelial Tight Junction Barrier in Murine Colitis and Attenuate Inflammatory Damage in Epithelial Organoids

Superoxide Dismutase 3-Transduced Mesenchymal Stem Cells Preserve Epithelial Tight Junction Barrier in Murine Colitis and Attenuate Inflammatory Damage in Epithelial Organoids

Superoxide dismutase 3 (SOD3), also known as extracellular superoxide dismutase, is an enzyme that scavenges reactive oxygen species (ROS). It has been reported that SOD3 exerts anti-inflammatory abilities in several immune disorders. However, the effect of SOD3 and the underlying mechanism in infla...

Full description

Bibliographic Details
Main Authors: Lee-Jung Tak, Hae-Young Kim, Won-Kook Ham, Gaurav Agrahari, Yoojin Seo, Ji Won Yang, Eun-Joo An, Chul Hwan Bang, Min Jung Lee, Hyung-Sik Kim, Tae-Yoon Kim
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
superoxide dismutase 3
mesenchymal stem cell
inflammatory bowel disease
epithelial tight junction
immunomodulation
intestinal epithelial organoid
Online Access:https://www.mdpi.com/1422-0067/22/12/6431

Similar Items

Similar Items