Significance of the Melanocortin 1 and Endothelin B Receptors in Melanocyte Homeostasis and Prevention of Sun-Induced Genotoxicity

Significance of the Melanocortin 1 and Endothelin B Receptors in Melanocyte Homeostasis and Prevention of Sun-Induced Genotoxicity

The membrane bound melanocortin 1 receptor (MC1R), and the endothelin B receptor (ENDBR) are two G-protein coupled receptors that play important roles in constitutive regulation of melanocytes and their response to ultraviolet radiation (UVR), the main etiological factor for melanoma. The human MC1...

Full description

Bibliographic Details
Main Authors: Zalfa A. Abdel-Malek, Viki Swope
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Genetics
Subjects:
DNA Repair
Melanocytes
Melanoma
Photoprotection
ultraviolet radiation
melanocortin 1 receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00146/full

Similar Items

Similar Items