Osteoclast-Like Cells in Aneurysmal Disease Exhibit an Enhanced Proteolytic Phenotype

Osteoclast-Like Cells in Aneurysmal Disease Exhibit an Enhanced Proteolytic Phenotype

Abdominal aortic aneurysm (AAA) is among the top 20 causes of death in the United States. Surgical repair is the gold standard for AAA treatment, therefore, there is a need for non-invasive therapeutic interventions. Aneurysms are more closely associated with the osteoclast-like catabolic degradatio...

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Bibliographic Details
Main Authors: Matthew J. Kelly, Kimihiro Igari, Dai Yamanouchi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
aneurysm
osteoclast-like cell (OLC)
hypoxia-inducible factor-1α (HIF-1α)
Online Access:https://www.mdpi.com/1422-0067/20/19/4689

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