Nanomaterials for Cardiac Tissue Engineering

End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and car...

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Main Authors: Devang R. Amin, Eric Sink, Suguna P. Narayan, Mostafa Abdel-Hafiz, Luisa Mestroni, Brisa Peña
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/21/5189
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spelling doaj-3b1fe87a1fc541ddaa6ee9e3c681d41d2020-11-25T04:07:47ZengMDPI AGMolecules1420-30492020-11-01255189518910.3390/molecules25215189Nanomaterials for Cardiac Tissue EngineeringDevang R. Amin0Eric Sink1Suguna P. Narayan2Mostafa Abdel-Hafiz3Luisa Mestroni4Brisa Peña5Department of Internal Medicine, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USADepartment of Internal Medicine, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USADepartment of Pathology, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USADepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, 12705 E. Montview Avenue, Suite 100, Aurora, CO 80045, USACardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, Aurora, CO 80045, USADepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, 12705 E. Montview Avenue, Suite 100, Aurora, CO 80045, USAEnd stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering.https://www.mdpi.com/1420-3049/25/21/5189cardiac tissue engineeringnanoparticlescarbon nanotubesgold nanorodscardiomyocyte regeneration
collection DOAJ
language English
format Article
sources DOAJ
author Devang R. Amin
Eric Sink
Suguna P. Narayan
Mostafa Abdel-Hafiz
Luisa Mestroni
Brisa Peña
spellingShingle Devang R. Amin
Eric Sink
Suguna P. Narayan
Mostafa Abdel-Hafiz
Luisa Mestroni
Brisa Peña
Nanomaterials for Cardiac Tissue Engineering
Molecules
cardiac tissue engineering
nanoparticles
carbon nanotubes
gold nanorods
cardiomyocyte regeneration
author_facet Devang R. Amin
Eric Sink
Suguna P. Narayan
Mostafa Abdel-Hafiz
Luisa Mestroni
Brisa Peña
author_sort Devang R. Amin
title Nanomaterials for Cardiac Tissue Engineering
title_short Nanomaterials for Cardiac Tissue Engineering
title_full Nanomaterials for Cardiac Tissue Engineering
title_fullStr Nanomaterials for Cardiac Tissue Engineering
title_full_unstemmed Nanomaterials for Cardiac Tissue Engineering
title_sort nanomaterials for cardiac tissue engineering
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2020-11-01
description End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering.
topic cardiac tissue engineering
nanoparticles
carbon nanotubes
gold nanorods
cardiomyocyte regeneration
url https://www.mdpi.com/1420-3049/25/21/5189
work_keys_str_mv AT devangramin nanomaterialsforcardiactissueengineering
AT ericsink nanomaterialsforcardiactissueengineering
AT sugunapnarayan nanomaterialsforcardiactissueengineering
AT mostafaabdelhafiz nanomaterialsforcardiactissueengineering
AT luisamestroni nanomaterialsforcardiactissueengineering
AT brisapena nanomaterialsforcardiactissueengineering
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