Heat Shock Factor 1 Prevents Age-Related Hearing Loss by Decreasing Endoplasmic Reticulum Stress

Heat Shock Factor 1 Prevents Age-Related Hearing Loss by Decreasing Endoplasmic Reticulum Stress

Endoplasmic reticulum (ER) stress is a common stress factor during the aging process. Heat shock factor 1 (HSF1) plays a critical role in ER stress; however, its exact function in age-related hearing loss (ARHL) has not been fully elucidated. The purpose of the present study was to identify the role...

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Bibliographic Details
Main Authors: Yun Yeong Lee, Eun Sol Gil, In Hye Jeong, Hantai Kim, Jeong Hun Jang, Yun-Hoon Choung
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
age-related hearing loss
apoptosis
endoplasmic reticulum stress
heat shock factor 1
heat shock protein
Online Access:https://www.mdpi.com/2073-4409/10/9/2454

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