Exploring new biological functions of amyloids: bacteria cell agglutination mediated by host protein aggregation.
Antimicrobial proteins and peptides (AMPs) are important effectors of the innate immune system that play a vital role in the prevention of infections. Recent advances have highlighted the similarity between AMPs and amyloid proteins. Using the Eosinophil Cationic Protein as a model, we have rational...
Main Authors: | Marc Torrent, David Pulido, M Victòria Nogués, Ester Boix |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3486885?pdf=render |
Similar Items
-
A theoretical approach to spot active regions in antimicrobial proteins
by: Boix Ester, et al.
Published: (2009-11-01) -
Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation
by: David Pulido, et al.
Published: (2016-04-01) -
The "CPC clip motif": a conserved structural signature for heparin-binding proteins.
by: Marc Torrent, et al.
Published: (2012-01-01) -
Forces between agglutinated bacteria
by: Purnell, Marjorie Axford
Published: (2016) -
The amyloid interactome: Exploring protein aggregation.
by: Konstantina V Biza, et al.
Published: (2017-01-01)