Intragraft Hyaluronan Increases in Association With Acute Lung Transplant Rejection

Intragraft Hyaluronan Increases in Association With Acute Lung Transplant Rejection

Background. Acute perivascular rejection (AR) is common in lung recipients and increases the risk for chronic lung allograft dysfunction (CLAD). Hyaluronan (HA), an extracellular matrix constituent, accumulates in experimental AR and can act as an innate immune agonist, breaking tolerance and potent...

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Main Authors: Haley P. Hostetler, MD, Megan L. Neely, PhD, Francine L. Kelly, PhD, John A. Belperio, MD, Marie Budev, MD, John M. Reynolds, MD, Pali D. Shah, MD, Lianne G. Singer, MD, Laurie D. Snyder, MD, Scott M. Palmer, MD, Jamie L. Todd, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-04-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001138

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