The origin and radiation of the phosphoprotein phosphatase (PPP) enzymes of Eukaryotes

Abstract Phosphoprotein phosphatase (PPP) enzymes are ubiquitous proteins involved in cellular signaling pathways and other functions. Here we have traced the origin of the PPP sequences of Eukaryotes and their radiation. Using a bacterial PPP Hidden Markov Model (HMM) we uncovered “BacterialPPP-Lik...

Full description

Bibliographic Details
Main Authors: David Kerk, Jordan F. Mattice, Mario E. Valdés-Tresanco, Sergei Yu Noskov, Kenneth K.-S. Ng, Greg B. Moorhead
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93206-8