HCV prevalence and predominant genotype in IV drug users

• Main Authors: Asad Andalibalshohada, Seyed Abdolrahim Rezaii, Farshid Abedi
• Format: Article
• Language: English
• Published: Mashhad University of Medical Sciences 2014-07-01
• Series: Reviews in Clinical Medicine
• Online Access: http://rcm.mums.ac.ir/pdf_3154_9d47b46007db6706af8a9c9c899e6dce.html

Hepatitis C virus (HCV) causes 308000 deaths due to liver cancer and 758000 deaths due to cirrhosis every year. Almost 170 million people have HCV infection around the world. Information regarding this virus helps us to determine the prevalence of other hepatitis C genotypes in population, especially in intravenous drug users. It is assumed that some genotypes are more common in certain areas or groups of people. A recent study strongly confirms the central role of injecting network traits, not only as a transmission factor but also as a predictor of HCV genotype and phylogenetic determination in different communities. Hepatitis C genotypes and subtypes have different prevalence considering the country. Risk factors such as transfusion, hemodialysis, root of acquisition and etc, are detected in intravenous drug users. Several conducted studies have investigated the prevalence, risk factors, and predominance of HCV genotypes infection in different parts of Iran.