miRNA-mediated functional changes through co-regulating function related genes.

BACKGROUND: MicroRNAs play important roles in various biological processes involving fairly complex mechanism. Analysis of genome-wide miRNA microarray demonstrate that a single miRNA can regulate hundreds of genes, but the regulative extent on most individual genes is surprisingly mild so that it i...

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Bibliographic Details
Main Authors: Jie He, Jin-fang Zhang, Can Yi, Qing Lv, Wei-dong Xie, Jian-na Li, Gang Wan, Kai Cui, Hsiang-fu Kung, Jennifer Yang, Burton B Yang, Yaou Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2962631?pdf=render