A microfluidic-based filtration system to enrich for bone marrow disseminated tumor cells from breast cancer patients.

A microfluidic-based filtration system to enrich for bone marrow disseminated tumor cells from breast cancer patients.

Disseminated tumors cells (DTCs) present in the bone marrow (BM) are believed to be the progenitors of distant metastatic spread, a major cause of mortality in breast cancer patients. To better understand the behavior and therapeutic vulnerabilities of these rare cell populations, unbiased methods f...

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Bibliographic Details
Main Authors: Sreeraj G Pillai, Chidananda M Siddappa, Cynthia Ma, Jackie Snider, Madhurima Kaushal, Mark A Watson, Rebecca Aft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246139

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