Oral angioleiomyoma: a case report and considerations on differential diagnosis

• Main Authors: Carlos Augusto Galvão Barboza, Fernanda Ginani, Airton Vieira Leite-Segundo, Uoston Holder da Silva
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Patologia Clínica 2013-12-01
• Series: Jornal Brasileiro de Patologia e Medicina Laboratorial
• Subjects: mucosa oral; neoplasias; angioleiomioma; maxila
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000600008&lng=en&tlng=en

Angioleiomyomas are benign mesenchymal tumors derived from smooth muscle, which rarely occur in the oral cavity. We report a case of an angioleiomyoma occurring in the maxillary gingiva. The lesion was painless, with a lobulated surface, fibrous in consistency, and firm upon palpation. Microscopic examination showed an encapsulated tumor mass composed of large vascular channels of varying calibers, surrounded by thick walls of irregularly arranged, spindle-shaped cells, which were immunopositive for smooth-muscle actin. It is sometimes difficult to differentiate an angioleiomyoma from other spindle-cell tumors, thus we emphasize its histological differential diagnosis.