The U-Rich Untranslated Region of the Hepatitis E Virus Induces Differential Type I and Type III Interferon Responses in a Host Cell-Dependent Manner

The U-Rich Untranslated Region of the Hepatitis E Virus Induces Differential Type I and Type III Interferon Responses in a Host Cell-Dependent Manner

Hepatitis E virus (HEV) is an important human pathogen causing both acute and chronic viral hepatitis E infection. Currently, the mechanisms of HEV replication and pathogenesis remain poorly understood. The innate immune response acts as the first line of defense during viral infection. The retinoic...

Full description

Bibliographic Details
Main Authors: Harini Sooryanarain, Connie L. Heffron, Xiang-Jin Meng
Format: Article
Language:English
Published: American Society for Microbiology 2020-01-01
Series:mBio
Subjects:
hepatitis e virus (hev)
u-rich region rna pamps
retinoic acid-inducible gene i (rig-i)
type i interferon (ifn)
type-iii ifn
Online Access:https://doi.org/10.1128/mBio.03103-19

Internet

https://doi.org/10.1128/mBio.03103-19

Similar Items