In silico Targeting, inhibition and analysis of polyketide synthase enzyme in Aspergillus ssp

In silico Targeting, inhibition and analysis of polyketide synthase enzyme in Aspergillus ssp

Aflatoxins are toxic and carcinogenic components produced by some Aspergillus species such as Aspergillus flavus. Polyketide synthases enzyme (PKS) plays a central role in aflatoxin s biosynthesis of in Aspergillus flavus, especially the product template (PT) domain, which controls the aldol cycliza...

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Bibliographic Details
Main Authors: Mai M. Labib, M.K. Amin, A.M. Alzohairy, M.M.A. Elashtokhy, O. Samir, I. Saleh, I.A. Arif, G.H. Osman, S.E. Hassanein
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Saudi Journal of Biological Sciences
Subjects:
Aflatoxin
PKS enzyme
Aflatoxin B1
PT domain
Docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20304976

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