Association between timing of peritoneal dialysis initiation and mortality in end-stage renal disease

Despite the widespread use of chronic dialysis for end-stage renal disease (ESRD), there is no consensus on the optimal timing of initiating renal replacement therapy. Over the past decade, a worldwide trend toward increasing glomerular filtration rate at the initiation of dialysis has been noted. H...

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Bibliographic Details
Main Authors: Yuan Peng, Xiao Yang, Wei Chen, Xue-Qing Yu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-03-01
Series:Chronic Diseases and Translational Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X17301111
Description
Summary:Despite the widespread use of chronic dialysis for end-stage renal disease (ESRD), there is no consensus on the optimal timing of initiating renal replacement therapy. Over the past decade, a worldwide trend toward increasing glomerular filtration rate at the initiation of dialysis has been noted. However, available data indicate that early dialysis has no survival benefit or is harmful. Peritoneal dialysis (PD) is one alternative for ESRD and has potential survival factors different from those of hemodialysis. The association between the timing of PD initiation and survival is unclear. This review examines the effect of the timing of dialysis on clinical outcomes in PD patients. Keywords: Peritoneal dialysis (PD), Initiation, Mortality, Glomerular filtration rate (GFR)
ISSN:2095-882X