The Hippocampal Vulnerability to Herpes Simplex Virus Type I Infection: Relevance to Alzheimer’s Disease and Memory Impairment

The Hippocampal Vulnerability to Herpes Simplex Virus Type I Infection: Relevance to Alzheimer’s Disease and Memory Impairment

Herpes simplex virus type 1 (HSV-1) as a possible infectious etiology in Alzheimer’s disease (AD) has been proposed since the 1980s. The accumulating research thus far continues to support the association and a possible causal role of HSV-1 in the development of AD. HSV-1 has been shown to induce ne...

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Bibliographic Details
Main Authors: Shin Jie Yong, Min Hooi Yong, Seong Lin Teoh, Tomoko Soga, Ishwar Parhar, Jactty Chew, Wei Ling Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
herpes simplex virus
hippocampus
neurotropism
Alzheimer’s disease
memory impairment
infectious etiology
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.695738/full

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