Effect of L-Glutathione Treatment during Somatic Cell Nuclear Transfer Procedures on the Subsequent Embryonic Development and DNA Methylation Status of Cloned Bovine Embryos

Effect of L-Glutathione Treatment during Somatic Cell Nuclear Transfer Procedures on the Subsequent Embryonic Development and DNA Methylation Status of Cloned Bovine Embryos

We investigate the effect of L-glutathione (GSH), an antioxidant, treatment during the somatic cell nuclear transfer (SCNT) procedures on the in vitro development and DNA methylation status of bovine SCNT embryos. Bovine in vitro matured (IVM) oocytes were enucleated and electrofused with a donor ce...

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Bibliographic Details
Main Authors: Hyo-Kyung Bae, Nam-Sik Yoon, In-Sun Hwang, Choon-Keun Park, Boo-Keun Yang, Hee-Tae Cheong
Format: Article
Language:English
Published: The Korean Society of Animal Reproduction and Biotechnology 2014-12-01
Series:Journal of Animal Reproduction and Biotechnology
Subjects:
somatic cell nuclear transfer
gsh
in vitro development
apoptosis
dna-methylation
Online Access:http://www.e-jarb.org/journal/view.html?uid=1450&vmd=Full

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