Synthesis of the furo[2,3-b]chromene ring system of hyperaspindols A and B

Synthesis of the furo[2,3-b]chromene ring system of hyperaspindols A and B

The synthesis of the unique furo[2,3-b]chromene ring system found in hyperaspidinols A and B, acylphloroglucinols from Hypericum chinense has been achieved in twelve steps. By comparison of the NMR spectra of the synthesized compounds with those of the natural products, a relative stereochemistry is...

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Bibliographic Details
Main Authors: Danielle L. Paterson, David Barker
Format: Article
Language:English
Published: Beilstein-Institut 2015-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
acylphloroglucinols
bicyclisation
furo[2,3-b]chromene
fused ketal
Online Access:https://doi.org/10.3762/bjoc.11.29
Description
Summary:The synthesis of the unique furo[2,3-b]chromene ring system found in hyperaspidinols A and B, acylphloroglucinols from Hypericum chinense has been achieved in twelve steps. By comparison of the NMR spectra of the synthesized compounds with those of the natural products, a relative stereochemistry is suggested, especially that of the ketal carbon.
ISSN:1860-5397

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