Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, m...

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Main Authors: Pasquale Mansueto, Aurelio Seidita, Giustina Vitale, Sebastiano Gangemi, Chiara Iaria, Antonio Cascio
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/735615
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spelling doaj-3acc826398c6405385447d8d7bcef9062020-11-25T00:17:14ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/735615735615Vitamin D Deficiency in HIV Infection: Not Only a Bone DisorderPasquale Mansueto0Aurelio Seidita1Giustina Vitale2Sebastiano Gangemi3Chiara Iaria4Antonio Cascio5Department of Internal Medicine and Biomedicine, University of Palermo, 90100 Palermo, ItalyDepartment of Internal Medicine and Biomedicine, University of Palermo, 90100 Palermo, ItalyDepartment of Internal Medicine and Biomedicine, University of Palermo, 90100 Palermo, ItalyDepartment of Human Pathology, University of Messina, 98125 Messina, ItalyInfectious Diseases Unit, Papardo-Piemonte Hospital, 98125 Messina, ItalyDepartment of Human Pathology, University of Messina, 98125 Messina, ItalyHypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.http://dx.doi.org/10.1155/2015/735615
collection DOAJ
language English
format Article
sources DOAJ
author Pasquale Mansueto
Aurelio Seidita
Giustina Vitale
Sebastiano Gangemi
Chiara Iaria
Antonio Cascio
spellingShingle Pasquale Mansueto
Aurelio Seidita
Giustina Vitale
Sebastiano Gangemi
Chiara Iaria
Antonio Cascio
Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
BioMed Research International
author_facet Pasquale Mansueto
Aurelio Seidita
Giustina Vitale
Sebastiano Gangemi
Chiara Iaria
Antonio Cascio
author_sort Pasquale Mansueto
title Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
title_short Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
title_full Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
title_fullStr Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
title_full_unstemmed Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
title_sort vitamin d deficiency in hiv infection: not only a bone disorder
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.
url http://dx.doi.org/10.1155/2015/735615
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AT giustinavitale vitaminddeficiencyinhivinfectionnotonlyabonedisorder
AT sebastianogangemi vitaminddeficiencyinhivinfectionnotonlyabonedisorder
AT chiaraiaria vitaminddeficiencyinhivinfectionnotonlyabonedisorder
AT antoniocascio vitaminddeficiencyinhivinfectionnotonlyabonedisorder
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