Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA.
Human cancer is caused by the interplay of mutations in oncogenes and tumor suppressor genes and inherited variations in cancer susceptibility genes. While many of the tumor initiating mutations are well characterized, the effect of genetic background variation on disease onset and progression is le...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4433219?pdf=render |