Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA.

Human cancer is caused by the interplay of mutations in oncogenes and tumor suppressor genes and inherited variations in cancer susceptibility genes. While many of the tumor initiating mutations are well characterized, the effect of genetic background variation on disease onset and progression is le...

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Bibliographic Details
Main Authors: Tobias Schmid, L Basten Snoek, Erika Fröhli, M Leontien van der Bent, Jan Kammenga, Alex Hajnal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4433219?pdf=render