Neuropathology and cognitive performance in self-reported cognitively healthy centenarians
Abstract With aging, the incidence of neuropathological hallmarks of neurodegenerative diseases increases in the brains of cognitively healthy individuals. It is currently unclear to what extent these hallmarks associate with symptoms of disease at extreme ages. Forty centenarians from the 100-plus...
Main Authors: | Andrea B. Ganz, Nina Beker, Marc Hulsman, Sietske Sikkes, Netherlands Brain Bank, Philip Scheltens, August B. Smit, Annemieke J. M. Rozemuller, Jeroen J. M. Hoozemans, Henne Holstege |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40478-018-0558-5 |
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