The efficacy of lacosamide as monotherapy and adjunctive therapy in focal epilepsy and its use in status epilepticus: clinical trial evidence and experience
Lacosamide (LCM) is approved for anticonvulsive treatment in focal epilepsy and exhibits its function through the slow inactivation of voltage-gated sodium channels (VGSCs). LCM shows comparable efficacy with other antiepileptic drugs (AEDs) licensed in the last decade: in three randomized placebo-c...
Main Authors: | Sebastian Bauer, Laurent M. Willems, Esther Paule, Christine Petschow, Johann Philipp Zöllner, Felix Rosenow, Adam Strzelczyk |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-02-01
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Series: | Therapeutic Advances in Neurological Disorders |
Online Access: | https://doi.org/10.1177/1756285616675777 |
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