In vitro effect of anti-β2 glycoprotein I antibodies on P-selectin expression, a marker of platelet activation

In vitro effect of anti-β2 glycoprotein I antibodies on P-selectin expression, a marker of platelet activation

Antiphospholipid antibodies (aPL) associated with thromboembolic events and/or pregnancy morbidity characterize the so-called antiphospholipid syndrome (APS). Beta2glycoprotein I (β2GPI) is the main target antigen for aPL, but the pathogenic role of anti-β2GPI antibodies (aβ2GPI) is still unclear. S...

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Bibliographic Details
Main Authors: A. Hoxha, M. Tonello, E. Falcinelli, S Giannini, A. Ruffatti, A. Bontadi, P. Gresele, L. Punzi
Format: Article
Language:English
Published: PAGEPress Publications 2012-03-01
Series:Reumatismo
Subjects:
Anti-β2Glicoprotein I antibodies, P-selectin, Platelet activation, Antiphospholipid syndrome
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/545

Internet

http://www.reumatismo.org/index.php/reuma/article/view/545

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