Prevalence and mechanism of fluoroquinolone resistance in clinical isolates of Proteus mirabilis in Japan

Fluoroquinolone (FQ) and cephalosporin (CEP) resistance among Enterobacteriaceae has been increasingly reported. FQ resistance occurs primarily through mutations in DNA gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE). CEP resistance in Enterobacteriaceae is mainly due to the production o...

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Bibliographic Details
Main Authors: Ryuichi Nakano, Akiyo Nakano, Michiko Abe, Noriyuki Nagano, Miwa Asahara, Taiji Furukawa, Yasuo Ono, Hisakazu Yano, Ryoichi Okamoto
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018337423