Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy

Hemophagocytic syndrome (HS) is a rare clinical condition characterized by fever and cytopenia due to phagocytosis of erythrocytes, leukocytes, platelets and their precursors in the bone marrow and other reticuloendothelial systems. The presence of HS can be associated with malignancies, infections...

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Bibliographic Details
Main Authors: Cemal Bes, Uğur Özensoy, Serdar Yanık, Pınar Memedoğlu, Ahsen Zeyrek, Mehmet Soy
Format: Article
Language:English
Published: PAGEPress Publications 2014-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:https://mjhid.org/index.php/mjhid/article/view/1938
Description
Summary:Hemophagocytic syndrome (HS) is a rare clinical condition characterized by fever and cytopenia due to phagocytosis of erythrocytes, leukocytes, platelets and their precursors in the bone marrow and other reticuloendothelial systems. The presence of HS can be associated with malignancies, infections, drugs and a variety of other medical disorders. We report a patient with seronegative spondyloarthropathy treated with sulfasalazine and was complicated by the occurrence of fever, facial erythema and pancytopenia. The patient was diagnosed with HS and successfully treated with corticosteroids.
ISSN:2035-3006