Terpenoids from Octocorals of the Genus Pachyclavularia

In this paper, we reviewed natural compounds isolated from octocorals belonging to the genus Pachyclavularia, including 20 cembrane-, 39 briarane-, and eight briarellin-related diterpenoids, and one secosterol. The chemical constituents of these 68 secondary metabolites, and their names, structures,...

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Main Authors:	Yu-Chia Chang, Jyh-Horng Sheu, Yang-Chang Wu, Ping-Jyun Sung
Format:	Article
Language:	English
Published:	MDPI AG 2017-12-01
Series:	Marine Drugs
Subjects:	Pachyclavularia octocoral cembrane briarane briarellin secosterol bioactivity
Online Access:	https://www.mdpi.com/1660-3397/15/12/382

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spelling	doaj-3a7d4acf9e1d4bc999d5567662361ed52020-11-25T00:09:01ZengMDPI AGMarine Drugs1660-33972017-12-01151238210.3390/md15120382md15120382Terpenoids from Octocorals of the Genus PachyclavulariaYu-Chia Chang0Jyh-Horng Sheu1Yang-Chang Wu2Ping-Jyun Sung3National Museum of Marine Biology and Aquarium, Pingtung 944, TaiwanDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, TaiwanGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, TaiwanNational Museum of Marine Biology and Aquarium, Pingtung 944, TaiwanIn this paper, we reviewed natural compounds isolated from octocorals belonging to the genus Pachyclavularia, including 20 cembrane-, 39 briarane-, and eight briarellin-related diterpenoids, and one secosterol. The chemical constituents of these 68 secondary metabolites, and their names, structures, and bioactivities, along with studies of their biological activities, are summarized in this review. Based on the literature, many of these compounds possess bioactivities, including anti-inflammation properties, cytotoxicity, and ichthyotoxicity, suggesting that they may have the potential to be developed into biomedical agents for treatment.https://www.mdpi.com/1660-3397/15/12/382Pachyclavulariaoctocoralcembranebriaranebriarellinsecosterolbioactivity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yu-Chia Chang Jyh-Horng Sheu Yang-Chang Wu Ping-Jyun Sung
spellingShingle	Yu-Chia Chang Jyh-Horng Sheu Yang-Chang Wu Ping-Jyun Sung Terpenoids from Octocorals of the Genus Pachyclavularia Marine Drugs Pachyclavularia octocoral cembrane briarane briarellin secosterol bioactivity
author_facet	Yu-Chia Chang Jyh-Horng Sheu Yang-Chang Wu Ping-Jyun Sung
author_sort	Yu-Chia Chang
title	Terpenoids from Octocorals of the Genus Pachyclavularia
title_short	Terpenoids from Octocorals of the Genus Pachyclavularia
title_full	Terpenoids from Octocorals of the Genus Pachyclavularia
title_fullStr	Terpenoids from Octocorals of the Genus Pachyclavularia
title_full_unstemmed	Terpenoids from Octocorals of the Genus Pachyclavularia
title_sort	terpenoids from octocorals of the genus pachyclavularia
publisher	MDPI AG
series	Marine Drugs
issn	1660-3397
publishDate	2017-12-01
description	In this paper, we reviewed natural compounds isolated from octocorals belonging to the genus Pachyclavularia, including 20 cembrane-, 39 briarane-, and eight briarellin-related diterpenoids, and one secosterol. The chemical constituents of these 68 secondary metabolites, and their names, structures, and bioactivities, along with studies of their biological activities, are summarized in this review. Based on the literature, many of these compounds possess bioactivities, including anti-inflammation properties, cytotoxicity, and ichthyotoxicity, suggesting that they may have the potential to be developed into biomedical agents for treatment.
topic	Pachyclavularia octocoral cembrane briarane briarellin secosterol bioactivity
url	https://www.mdpi.com/1660-3397/15/12/382
work_keys_str_mv	AT yuchiachang terpenoidsfromoctocoralsofthegenuspachyclavularia AT jyhhorngsheu terpenoidsfromoctocoralsofthegenuspachyclavularia AT yangchangwu terpenoidsfromoctocoralsofthegenuspachyclavularia AT pingjyunsung terpenoidsfromoctocoralsofthegenuspachyclavularia
_version_	1725413394454937600

Terpenoids from Octocorals of the Genus Pachyclavularia

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