GPX8 is transcriptionally regulated by FOXC1 and promotes the growth of gastric cancer cells through activating the Wnt signaling pathway

Abstract Background Glutathione Peroxidase 8 (GPX8) as a member of the glutathione peroxidase (GPx) family plays an important role in anti-oxidation. Besides, dysregulation of GPX8 has been found in gastric cancer, but its detailed molecular mechanism in gastric cancer has not been reported. Methods...

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Bibliographic Details
Main Authors: Hong Chen, Lu Xu, Zhi-li Shan, Shu Chen, Hao Hu
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-020-01692-z