Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles

Membrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dynamics within the membrane. Here authors report the use of fluorescent magnetic nanoparticles to track membrane molecules and to manipulate t...

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Main Authors: Jia Hui Li, Paula Santos-Otte, Braedyn Au, Jakob Rentsch, Stephan Block, Helge Ewers
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18087-3
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spelling doaj-3a658df9ef4843eda3115f093781a4222021-08-29T11:40:32ZengNature Publishing GroupNature Communications2041-17232020-08-011111710.1038/s41467-020-18087-3Directed manipulation of membrane proteins by fluorescent magnetic nanoparticlesJia Hui Li0Paula Santos-Otte1Braedyn Au2Jakob Rentsch3Stephan Block4Helge Ewers5Institut für Biochemie, Freie Universität BerlinInstitut für Biochemie, Freie Universität BerlinInstitut für Biochemie, Freie Universität BerlinInstitut für Biochemie, Freie Universität BerlinInstitut für Chemie, Freie Universität BerlinInstitut für Biochemie, Freie Universität BerlinMembrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dynamics within the membrane. Here authors report the use of fluorescent magnetic nanoparticles to track membrane molecules and to manipulate their movement and pull membrane components laterally through the membrane with femtonewton-range forces.https://doi.org/10.1038/s41467-020-18087-3
collection DOAJ
language English
format Article
sources DOAJ
author Jia Hui Li
Paula Santos-Otte
Braedyn Au
Jakob Rentsch
Stephan Block
Helge Ewers
spellingShingle Jia Hui Li
Paula Santos-Otte
Braedyn Au
Jakob Rentsch
Stephan Block
Helge Ewers
Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
Nature Communications
author_facet Jia Hui Li
Paula Santos-Otte
Braedyn Au
Jakob Rentsch
Stephan Block
Helge Ewers
author_sort Jia Hui Li
title Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
title_short Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
title_full Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
title_fullStr Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
title_full_unstemmed Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
title_sort directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-08-01
description Membrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dynamics within the membrane. Here authors report the use of fluorescent magnetic nanoparticles to track membrane molecules and to manipulate their movement and pull membrane components laterally through the membrane with femtonewton-range forces.
url https://doi.org/10.1038/s41467-020-18087-3
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AT jakobrentsch directedmanipulationofmembraneproteinsbyfluorescentmagneticnanoparticles
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