Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles

Membrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dynamics within the membrane. Here authors report the use of fluorescent magnetic nanoparticles to track membrane molecules and to manipulate t...

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Bibliographic Details
Main Authors: Jia Hui Li, Paula Santos-Otte, Braedyn Au, Jakob Rentsch, Stephan Block, Helge Ewers
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18087-3
Description
Summary:Membrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dynamics within the membrane. Here authors report the use of fluorescent magnetic nanoparticles to track membrane molecules and to manipulate their movement and pull membrane components laterally through the membrane with femtonewton-range forces.
ISSN:2041-1723