Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and beh...

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Bibliographic Details
Main Authors: Sophie Leclercq, Firoz M. Mian, Andrew M. Stanisz, Laure B. Bindels, Emmanuel Cambier, Hila Ben-Amram, Omry Koren, Paul Forsythe, John Bienenstock
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15062
Description
Summary:There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and behaviour.
ISSN:2041-1723

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