Sore Throat Progressing to Embolic Sepsis: A Case of Lemierre’s Syndrome

Lemierre’s syndrome is a rare clinical syndrome defined as oropharyngeal sepsis, thrombophlebitis of the internal jugular vein and septic thombo-emboli. It is typically encountered in young, immunocompetent individuals, with a mean incident age of 20 years. The organism that is most commonly associa...

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Bibliographic Details
Main Authors: Jacquelyn Dirks, Dennis Bowie
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2010/950709
Description
Summary:Lemierre’s syndrome is a rare clinical syndrome defined as oropharyngeal sepsis, thrombophlebitis of the internal jugular vein and septic thombo-emboli. It is typically encountered in young, immunocompetent individuals, with a mean incident age of 20 years. The organism that is most commonly associated is an anaerobic Gram-negative bacterium: Fusobacterium species. The defined treatment course is at least six weeks of antibiotics, with the role of anticoagulation being unclear. The present article documents a case of Lemierre’s syndrome complicated by acute renal failure and loculated pleural effusion in an otherwise healthy 16-year-old patient.
ISSN:1198-2241